Genetics

The regional Genetics Centre is an integrated service consisting of the Guy's and St Thomas' Clinical Genetics department and the GSTS DNA, Cytogenetics and Biochemical Genetics Laboratories.

All three laboratories are CPA accredited. The Genetics Centre provides a service to the former South East Thames NHS region, with an estimated population of 3.8 million. It is a member of the South East England Genetics Network (SEEGen), which is a consortium comprising laboratories and genetic clinics within South East England serving a total population of 14.2 million.

In addition, the laboratories receive a large number of national and international referrals for an increasing number of highly specialised genetic tests.

Array Comparative Genomic Hybridisation (aCGH)

For the detection of chromosome imbalance, G-banded chromosome analysis has been superseded by a higher resolution technique called array CGH. Array CGH can only be carried out on DNA extracted from a blood sample in EDTA. The array CGH test also includes all the regions of the genome known to be associated with submicroscopic deletions and duplications previously tested using additional MLPA and FISH tests (e.g. 22q11). ...  [more]

Oncology Cytogenetics

The Oncology Cytogenetics service is a leading centre for high quality G-banded and fluorescence in-situ hybridisation (FISH) analysis of a wide range of malignant diseases....  [more]

Genetics contact details

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Biochemical Laboratory

The Biochemical Genetics Laboratory is a Supraregional Assay Service (SAS). ...  [more]

Cytogenetics Laboratory

The Cytogenetics Laboratory is a leading provider of high quality comprehensive services for both constitutional and acquired chromosome abnormalities....  [more]

DNA Laboratory

The DNA Laboratory provides a clinical molecular genetics service for several genetic disorders, including Duchenne muscular dystrophy, congenital muscular dystrophies, Huntington disease, inherited predisposition to breast cancer and spinal muscular atrophy. ...  [more]